Molecular Formula | C23H30O3 |
Molar Mass | 354.49 |
Density | 1.20 |
Melting Point | 172 °C(Solv: isopropyl ether (108-20-3)) |
Boling Point | 508.9±50.0 °C(Predicted) |
pKa | 13.01±0.40(Predicted) |
Physical and Chemical Properties | Crystallization. Melting point 158-162 ℃. |
Use | an intermediate of trienol. |
production method | β-naphthol may be etherified with methanol and subjected to catalytic hydrogenation and oxidation, 6-methoxynaphthalenone is formed, then (keto) is added with vinyl magnesium bromide and with 1-ethyl-2, 5-cyclopentanedione condensation and cyclization of 3-methoxy-18-methylestrene-1, 3,5(10),8,14-penten-17-one, then catalytically hydrogenates (14-position double bond) and reduces to obtain 17-hydroxy-3-methoxy-18-methyl-19-desmethylandrosterin-2, 5(10) Diene, finally by biological oxidation (17-hydroxyl), (17-position) alkynylation, hydrolysis (to 3-position Methoxy), (perbrominated pyridinium bromide) addition and elimination (dehydrobromination to form a 4,9-position double bond), (3-position ketone group with ethylene glycol) ketalization to prepare the product. |